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C-Peptide Summary

Description: The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.

Also Known As: C-Peptide, Proinsulin; Connecting Peptide; C Peptide; C Peptide, Proinsulin; Proinsulin C Peptide Show All >>

Networked: 2128 relevant articles (86 outcomes, 235 trials/studies) for this Bio-Agent

Key Diseases for which C-Peptide is Relevant

  1. Type 1 Diabetes Mellitus (Autoimmune Diabetes) : 21 outcomes 39 studies in 206 results
  2. Type 2 Diabetes Mellitus (MODY) : 9 outcomes 25 studies in 203 results
  3. Insulin Resistance : 8 outcomes 18 studies in 283 results
  4. Hyperglycemia : 8 outcomes 11 studies in 121 results
  5. Hyperinsulinism (Hyperinsulinemia) : 6 outcomes 10 studies in 138 results
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Drugs Related to C-Peptide

  1. Insulin (Novolin)
  2. Glucose (Dextrose)
  3. Glucagon (Glukagon)
  4. Triglycerides (Triacylglycerol)
  5. Glyburide (Glibenclamide)
  6. Cyclosporine (Ciclosporin)
  7. Arginine (L-Arginine)
  8. Glipizide (Glucotrol)
  9. Proinsulin
  10. Insulin-Like Growth Factor I (IGF-1)
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Therapies Related to C-Peptide

  1. Transplantation (Transplant Recipients)
  2. Plasmapheresis
  3. Female Contraceptive Devices (Vaginal Ring)
  4. Cardiopulmonary Resuscitation (CPR)
  5. Transplants (Transplant)
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