[Renal damage caused by Rhupus syndrome associated with anti-neutrophil cytoplasmic antibodies vasculitis and cryoglobulinemia].

Abstract

We analyzed the clinicopathological characteristics of one patient with Rhupus syndrome associated nephropathy in Peking University People's Hospital, and reviewed the related literature. The patient was a middle aged female. She developed rheumatoid arthritis first, and then manifested mild systemic lupus erythematosus together with positive anti-neutrophil cytoplasmic antibodies (ANCA) and cryoglobulinemia several years later. The renal biopsy was performed and manifested as lupus nephritis. The transmission electron microscopy revealed cryoglobulinemia associated renal damage. This report shows that the clinicopathological characteristics in patients with Rhupus syndrome associated nephropathy are complicated. The renal pathology can be used as a diagnostic tool.

• Authors: Xin-ju Zhao, Tao Wei, Bao Dong, Yuan Jia, Mei Wang
• Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences (Beijing Da Xue Xue Bao Yi Xue Ban) Vol. 47 Issue 5 Pg. 870-4 (Oct 18 2015) ISSN: 1671-167X [Print] China
• PMID: 26474633 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't, Review)

Chemical References

• Antibodies, Antineutrophil Cytoplasmic

Topics

• Antibodies, Antineutrophil Cytoplasmic
• Arthritis, Rheumatoid
• Beijing
• Cryoglobulinemia (physiopathology)
• Female
• Humans
• Kidney (pathology)
• Lupus Erythematosus, Systemic
• Lupus Nephritis
• Middle Aged
• Vasculitis